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Recent papers

Induction of toxicity in human colon cells and organoids by size- and composition-dependent road dust RSC Advances 2023, 13 (5), 2833–2840.

Orally bioavailable BTK PROTAC active against wild-type and C481 mutant BTKs in human lymphoma CDX mouse models Blood Advances 2023, 7 (1), 92–105.

N-Cyano sulfilimine functional group as a nonclassical amide bond bioisostere in the design of a potent analogue to anthranilic diamide insecticide RSC Advances 2023, 13 (3), 2004–2009.

Investigation of benzimidazole anthelmintics as oral anticancer agents Bulletin of the Korean Chemical Society 2022, 43 (5), 750–756.

Gold nanoparticle-assisted delivery of brain-derived neurotrophic factor to cerebral organoids Nano Research 2022, 15 (4), 3099–3105.

A Comparative Systematic Analysis of The Influence of Microplastics on Colon Cells, Mouse and Colon Organoids Tissue Engineering and Regenerative Medicine 2022.

Ocular tropism of SARS-CoV-2 in animal models with retinal inflammation via neuronal invasion following intranasal inoculation Nature Communications 2022, 13 (1).

SARS-CoV-2 Infection of Microglia Elicits Proinflammatory Activation and Apoptotic Cell Death Microbiology Spectrum 2022, 10 (3).

Immunological and Pathological Peculiarity of Severe Acute Respiratory Syndrome Coronavirus 2 Beta Variant Microbiology Spectrum 2022, 10 (5).

Comparison of plaque size, thermal stability, and replication rate among SARS-CoV-2 variants of concern Viruses 2022, 14 (1).

Dynamics of Viral and Host 3D Genome Structure upon Infection Journal of Microbiology and Biotechnology 2022, 32 (12), 1515–1526.

Early postnatal serotonin modulation prevents adult-stage deficits in Arid1b-deficient mice through synaptic transcriptional reprogramming Nature Communications 2022, 13 (1), 5051–0.

GCN5 maintains muscle integrity by acetylating YY1 to promote dystrophin expression Journal of Cell Biology 2022, 221 (2).

Protein interactome and cell-type expression analyses reveal that cytoplasmic FMR1-interacting protein 1 (CYFIP1), but not CYFIP2, associates with astrocytic focal adhesion Journal of Neurochemistry 2022.

Pyrazolo[3,4-d]pyrimidine derivatives as irreversible Bruton's tyrosine kinase inhibitors Bulletin of the Korean Chemical Society 2022, 43 (4), 577–584.

Discovery of harmalanium halides as anti-ovarian cancer agents Bulletin of the Korean Chemical Society 2022, 43 (4), 559–563.

Structure-activity relationship analysis of novel GSPT1 degraders based on benzotriazinone scaffold and its antitumor effect on xenograft mouse model Bioorganic Chemistry 2022, 127.

Phenyl Ethers from the Marine-Derived Fungus Aspergillus tabacinus and Their Antimicrobial Activity Against Plant Pathogenic Fungi and Bacteria ACS Omega 2022, 7 (37), 33273–33279.

Curvicollide D, a new modified γ-lactone from the culture broth of Albifimbria verrucaria and its antifungal activity against plant pathogenic fungi Journal of Antibiotics 2022.

Characterization of Alternaria porri causing onion purple blotch and its antifungal compound magnolol identified from Caryodaphnopsis baviensis PLoS ONE 2022, 17 (1 January).

Biological Control Potential of Penicillium brasilianum against Fire Blight Disease Plant Pathology Journal 2022, 38 (5), 461–471.

Development of an Efficient Screening Method for Chinese Cabbage Cultivars Resistant to Alternaria brassicicola and Determination of Their Resistance Characteristics Horticultural Science and Technology 2022, 40 (1), 94–108.

A Bioassay for Testing Garlic Resistance to Leaf Blight Caused by Stemphylium vesicarium Horticultural Science and Technology 2022, 40 (3), 324–337.

Acid-Catalyzed Hydrolysis and Intramolecular Cyclization of N-Cyano Sulfoximines for the Synthesis of Thiadiazine 1-Oxides ACS Omega 2022, 7 (2), 2160–2169.

Synthesis and biological evaluation of 2-benzylaminoquinazolin-4(3H)-one derivatives as a potential treatment for SARS-CoV-2 Bulletin of the Korean Chemical Society 2022, 43 (3), 412–416.

Anticoronaviral Activity of the Natural Phloroglucinols, Dryocrassin ABBA and Filixic Acid ABA from the Rhizome of Dryopteris crassirhizoma by Targeting the Main Protease of SARS-CoV-2 Pharmaceutics 2022, 14 (2).

Anti-neuroinflammatory Effects and Brain Pharmacokinetic Properties of Selonsertib, an Apoptosis signal-regulating Kinase 1 Inhibitor, in mice Neurochemical Research 2022.

Discovery and synthesis of 1,2,4-oxadiazole derivatives as novel inhibitors of Zika, dengue, Japanese encephalitis, and classical swine fever virus infections Archives of Pharmacal Research 2022, 45 (4), 280–293.

PredMS: a random forest model for predicting metabolic stability of drug candidates in human liver microsomes Bioinformatics 2022, 38 (2), 364–368.

Antibacterial Activity against Clinical Isolates and In Vivo Efficacy of Coralmycins Antibiotics 2022, 11 (7).

Pharmacokinetics and Tissue Distribution of 13 C-Labeled Succinic Acid in Mice Nutrients 2022, 14 (22).

KR-31831 improves survival and protects hematopoietic cells and radiosensitive tissues against radiation-induced injuries in mice Biomedicine and Pharmacotherapy 2022, 146.

CDI Exerts Anti-Tumor Effects by Blocking the FoxM1-DNA Interaction Biomedicines 2022, 10 (7).

Identification and New Indication of Melanin-Concentrating Hormone Receptor 1 (MCHR1) Antagonist Derived from Machine Learning and Transcriptome-Based Drug Repositioning Approaches International Journal of Molecular Sciences 2022, 23 (7).

Novel allosteric glutaminase 1 inhibitors with macrocyclic structure activity relationship analysis Bioorganic and Medicinal Chemistry Letters 2022, 75.

Chronicles of EGFR Tyrosine Kinase Inhibitors: Targeting EGFR C797S Containing Triple Mutations Biomolecules and Therapeutics 2022, 30 (1), 19–27.

Discovery of BET specific bromodomain inhibitors with a novel scaffold Bioorganic and Medicinal Chemistry 2022, 72.

PCW-A1001, AI-assisted de novo design approach to design a selective inhibitor for FLT-3(D835Y) in acute myeloid leukemia Frontiers in Molecular Biosciences 2022, 9.

PCW-1001, a Novel Pyrazole Derivative, Exerts Antitumor and Radio-Sensitizing Activities in Breast Cancer Frontiers in Oncology 2022, 12.

Enteroviral replication inhibition by N-Alkyl triazolopyrimidinone derivatives through a non-capsid binding mode Bioorganic and Medicinal Chemistry Letters 2022, 64.

Characterization of Fusarium asiaticum and F. graminearum isolates from gramineous weeds in the proximity of rice fields in Korea Plant Pathology 2022, 71 (5), 1164–1173.

Generation of human tonsil epithelial organoids as an ex vivo model for SARS-CoV-2 infection Biomaterials 2022, 283.

The preclinical efficacy of the novel hypomethylating agent NTX-301 as a monotherapy and in combination with venetoclax in acute myeloid leukemia Blood Cancer Journal 2022, 12 (4).

The efficacy of a 2,4-diaminoquinazoline compound as an intranasal vaccine adjuvant to protect against influenza A virus infection in vivo Journal of Microbiology 2022, 60 (5), 550–559.

Development of Potent Immune Modulators Targeting Stimulator of Interferon Genes Receptor Journal of Medicinal Chemistry 2022, 65 (7), 5407–5432.

Cereblon contributes to cardiac dysfunction by degrading Cav1.2α European Heart Journal 2022, 43 (20), 1973–1989.

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